Defense Notices

The RF spectrum is a precious, finite resource with ever-increasing demand. Consequently, the mandate to be a "good spectral neighbor" is in direct conflict with the requirements for high-performance sensing where correlation error is fundamentally limited. As such, matched-filter radar performance is often sidelobe-limited with estimation error being constrained by the time-bandwidth (TB) of the collective emission. The methods developed here seek to bridge this gap between idealized radar performance and practical utility via waveform design.    

Estimation error becomes more complex when employing pulse-agility. In doing so, range-sidelobe modulation (RSM) spreads energy across Doppler, rendering traditional methods ineffective. To address this, the gradient-based complementary-FM framework was developed to produce complementary sidelobe cancellation (CSC) after coherently combining subsets within a pulse-agile emission. In contrast to the majority of complementary signals, explored via phase-coding, these Comp-FM waveform subsets achieve CSC while preserving hardware-compatibility since they are FM (though design distortion is never completely avoided). Although Comp-FM addressed practicality via hardware amenability, CSC was localized to zero-Doppler. This work expands the Comp-FM notion to a Doppler-generalized (DG) framework, extending the cancellation condition to an arbitrary span. The same framework can likewise be employed to jointly optimize an entire coherent processing interval (CPI) to minimize RSM within the radar point-spread-function (PSF), thereby generalizing the notion of complementarity and introducing the potential for cognitive operation if sufficient scattering knowledge is available a-priori.          

Sensing with a single emitter is limited by self-inflicted error alone (e.g., clutter, sidelobes), while MIMO systems must additionally contend with the cross-responses from emitters operating concurrently (e.g., simultaneously, spatially proximate, in a shared spectrum), further degrading radar sensitivity. Now, total correlation error is dictated by the overlapping TB (i.e., how coincident are the signals) and number of operating emitters, compounding difficulty to estimate if left unaddressed. As such, the determination of "orthogonal waveforms" comprises a large portion of MIMO literature, though remains a phenomenological misnomer for pulsed emissions. Here, the notion of complementary-FM is applied to a multi-emitter context in which transmitter-amenable quasi-orthogonal subsets, occupying the same spectral band, are produced via a similar gradient-based approach. To further practicalize these MIMO-Comp-FM waveform subsets, the same "DG" approach described above, addressing the otherwise-default Doppler-induced degradation of complementary signals, is applied. In doing so, Doppler-independent separability and complementarity greatly improves estimation sensitivity for multi-emitter systems. 

This MIMO-Comp-FM framework is developed for standard matched filter processing. Coupling this framework with a "DG" form of the previously explored MIMO-MiCRFt is also investigated, illustrating the added benefit of pairing optimized subsets with similarly calibrated processing. 

Each of these methods is developed to address unique and increasingly complex sources of estimation error. All approaches are initially developed and evaluated via simulated analysis where ground-truth is known. Then, despite hardware-induced distortion being unavoidable, the MIMO-Comp-FM framework is confirmed via loopback measurements to preserve the majority of CSC that was observed in simulation. Finally, open-air demonstration of each approach validates practical utility on a radar system.

Metagenomic sequencing has become a central paradigm for studying complex microbial communities and their interactions with the host, with emerging applications in clinical prediction and disease modeling. In this work, we first investigate two representative application scenarios: predicting immune checkpoint inhibitor response in non-small cell lung cancer using gut microbial signatures, and characterizing host–microbiome interactions in neonatal systems. The proposed reference-free neural network captures both compositional and functional signals without reliance on reference genomes, while the neonatal study demonstrates how environmental and genetic factors reshape microbial communities and how probiotic intervention can mitigate pathogen-induced immune activation.

These studies highlight both the promise and the inherent difficulty of metagenomic analysis: transforming raw sequencing data into clinically actionable insights remains an algorithmically fragmented and computationally intensive process. This challenge arises from two key limitations: the lack of a unified algorithmic foundation for sequence alignment and the absence of systematic approaches for selecting and organizing analytical tools. Motivated by these challenges, we present a unified computational framework for metagenomic analysis that integrates complementary algorithmic and systems-level solutions.

First, to resolve fragmentation at the alignment level, we develop the Versatile Alignment Toolkit (VAT), a unified algorithmic system for biological sequence alignment across diverse applications. VAT introduces an asymmetric multi-view k-mer indexing scheme that integrates multiple seeding strategies within a single architecture and enables dynamic seed-length adjustment via longest common prefix (LCP)–based inference without re-indexing. A flexible seed-chaining mechanism further supports diverse alignment scenarios, including collinear, rearranged, and split alignments. Combined with a hardware-efficient in-register bitonic sorting algorithm and dynamic index-loading strategy, VAT achieves high efficiency and broad applicability across read mapping, homology search, and whole-genome alignment. Second, to address the challenge of tool selection and pipeline construction, we develop SNAIL, a natural language processing system for automated recognition of bioinformatics tools from large-scale and rapidly growing scientific literature. By integrating XGBoost and Transformer-based models such as SciBERT, SNAIL enables structured extraction of analytical tools and supports automated, reproducible pipeline construction.

Together, this work establishes a unified framework that is grounded in real-world applications and addresses key bottlenecks in metagenomic analysis, enabling more efficient, scalable, and clinically actionable workflows.

Conventional computer vision relies on spatially resolved, human-interpretable images, which inherently expose sensitive information and raise privacy concerns. In this study, we explore an alternative paradigm based on lensless imaging, where scenes are captured as diffraction patterns governed by the point spread function (PSF). Although unintelligible to humans, these measurements encode structured, distributed information that remains useful for computational inference. 

We propose a unified framework for privacy-preserving vision that operates directly on lensless sensor measurements by leveraging their frequency-domain and phase-encoded properties. The framework is developed along two complementary directions. First, we enable reconstruction-free inference by exploiting the intrinsic obfuscation of lensless data. We show that semantic tasks such as classification can be performed directly on diffraction patterns using models tailored to non-local, phase-scrambled representations. We further design lensless-aware architectures and integrate them into practical pipelines, including a Swin Transformer-based steganographic framework (DiffHide) for secure and imperceptible information embedding. To assess robustness, we formalize adversarial threat models and develop defenses against learning-based reconstruction attacks, particularly GAN-driven inversion. Second, we investigate the limits of privacy by studying the reconstructability of lensless measurements without explicit knowledge of the forward model. We develop learning-based reconstruction methods that approximate the inverse mapping and analyze conditions under which sensitive information can be recovered. Our results demonstrate that lensless measurements enable effective vision tasks without reconstruction, while providing a principled framework to evaluate and mitigate privacy risks. 

Coherent wavelength-division multiplexed (WDM) optical fiber systems have become the primary transmission technology for high-capacity data networks, driven by the explosive bandwidth demand of cloud computing, streaming services, and large-scale artificial intelligence training infrastructure. This dissertation investigates two fundamental aspects of digital coherent fiber optic systems under the unifying theme of source and monitoring: the design of multi-wavelength optical sources compatible with high-order coherent detection, and the leveraging of fiber Kerr-effect nonlinearity at the coherent receiver to perform physical-layer link health monitoring and to assess inherent security vulnerabilities — both achieved through digital signal processing of the received complex optical field without dedicated hardware.

We begin by addressing the multi-wavelength transmitter challenge in WDM coherent systems. Existing quantum-dot, quantum-dash, and quantum-well based optical frequency comb (OFC) sources share a common limitation: individual comb line linewidths in the tens of MHz range caused by low output power levels of 1–20 mW, making them incompatible with high-order coherent detection. We demonstrate coherent system application of a single-section InGaAsP QW Fabry-Perot laser diode with greater than 120 mW optical power at the fiber pigtail and 36.14 GHz mode spacing. The high optical power per mode produces Lorentzian equivalent linewidths below 100 kHz — compatible with 16-QAM carrier phase recovery without optical phase locking. Experimental results obtained using a commercial Ciena WaveLogic-Ai coherent transceiver demonstrate 20-channel WDM transmission over 78.3 km of standard single-mode fiber with all channels below the HD-FEC threshold of 3.8 × 10⁻³ at 30 GBaud differential-coded 16-QAM, corresponding to an aggregate capacity of 2.15 Tb/s from a single laser device.

After investigating the QW Fabry-Perot laser as a multi-wavelength source for coherent WDM transmission, we leverage the coherent receiver DSP to exploit fiber Kerr-effect nonlinearity for longitudinal power profile estimation, enabling reconstruction of the signal power distribution P(z) along the full multi-span link without dedicated hardware or traffic interruption. We propose a modified enhanced regular perturbation (ERP) method that corrects two independent physical error sources of the standard RP1 least-squares baseline: the accumulated nonlinear phase rotation, and the dispersion-mediated phase-to-intensity conversion — a second bias source not addressed by prior methods. The RP1 method produces mean absolute error (MAE) that scales quadratically with span count, growing to 1.656 dB at 10 spans and 3 dBm. The modified ERP reduces this to 0.608 dB — an improvement that grows consistently with link length, confirming increasing advantage in the long-haul regime. Extension to WDM through an XPM-aware per-channel formulation achieves MAE of 0.113–0.419 dB across 150–500 km link lengths.

In addition to its role in enabling DSP-based longitudinal power profile estimation, the fiber Kerr-effect nonlinearity is shown to give rise to an inherent physical-layer security vulnerability in coherent WDM systems. We show that an eavesdropper co-tenanting a shared fiber — transmitting a continuous-wave probe at a wavelength adjacent to the legitimate signal — can capture the XPM-induced waveform at the fiber output and apply a bidirectional gated recurrent unit neural network, trained on split-step Fourier method simulation data, to reconstruct the transmitted symbol sequence without physical fiber access and without perturbing the legitimate signal. This eavesdropping mechanism is experimentally validated using a commercial Ciena WaveLogic-Ai coherent transceiver for ASK, BPSK, QPSK, and 16-QAM modulation formats at 4.26 GBaud and 8.56 GBaud over one- and two-span 75 km fiber systems, achieving zero symbol errors under high-OSNR conditions. Noise-aware training over OSNR from 20 to 60 dB maintains symbol error rate below 10⁻² for OSNR above 25–30 dB.

Together, these three contributions demonstrate that the coherent fiber optic system is a versatile physical instrument extending well beyond its role as a data transmission medium. The coherent receiver infrastructure — deployed for high-order modulation and data recovery — simultaneously enables the high-power OFC laser to serve as a practical multi-wavelength transmitter source, and provides the complex field measurement capability through which fiber Kerr-effect nonlinearity can be exploited constructively for distributed link monitoring and, as a direct consequence, reveals an inherent physical-layer security exposure in shared fiber infrastructure. This unified perspective on the coherent system as both a transmission platform and a general-purpose measurement instrument has direct relevance to the design of spectrally efficient, self-monitoring, and physically secure optical interconnects for next-generation AI computing networks.